Li T, Ning Z, Yang Z, Zhai R, Xu W, Ying K, Wang Y, Chen Y, Shen X (2020). Total genetic contribution assessment across the human genome. Nature Communications, 12, 1845.
R package HDL for precise genetic correlation estimation
Ning Z, Pawitan Y, Shen X (2020). High-definition likelihood inference of genetic correlations across human complex traits. Nature Genetics, 52: 859–864.
R package MultiABEL for multi-trait genome-wide association analysis
Shen X, Klaric L, Sharapov S, Mangino M, Ning Z, Wu D, Trbojevic-Akmacic I, Pucic-Bakovic M, Rudan I, Polasek O, Hayward C, Spector TD, Wilson JF, Lauc G, Aulchenko YS (2017): Multivariate discovery and replication of five novel loci associated with Immunoglobulin G N-glycosylation. Nature Communications, 8, 447.
R package SOJO for fine-mapping using LASSO based on GWAS summary statistics
Ning Z, Lee Y, Joshi PK, Wilson JF, Pawitan Y, Shen X (2017): A selection operator for summary association statistics reveals allelic heterogeneity of complex traits. American Journal of Human Genetics, 101(6): 903-912.
R package hglm for generalized linear models with random effects
GenABEL::polygenic_hglm() procedure for fitting polygenic models